Symposium Welcome


June 12-13, 2018

Nationwide Children’s Hospital – Columbus, Ohio


On behalf of the Center for Pediatric Trauma Research and the Trauma Program at Nationwide Children’s Hospital and The Ohio State University, it brings us great pleasure to announce the Global Symposium of Innovation in Trauma Research Methods to be held June 12-13, 2018 at Nationwide Children’s Hospital in Columbus, Ohio, USA. This event will unite distinguished researchers from around the world to discuss the latest developments in statistical and research methodologies available for use in trauma research.

In addition to keynote addresses and panel discussions from an interdisciplinary group of renowned experts, there will be presentations selected from submitted abstracts, both in oral and poster format. We invite you to submit abstracts describing or demonstrating innovative methodologies.

We aim to bring together scientists and clinicians from universities, hospitals, and research institutes  to share and discuss content in the following areas: Observational and Medical Record Data, Causal Inference Methods, Cohort and Longitudinal Data Analytics, Adaptive Clinical Trial Designs, Imaging, and Virtual Reality.

Thank you in advance, for sharing your time and expertise with us. We look forward to welcoming you to Ohio.

Henry Xiang, MD, MPH, PhD            Steve MacEachern, PhD          Bo Lu, PhD



The Center for Pediatric Trauma Research (CPTR) at Nationwide Children’s Hospital conducts research to support global efforts in achieving the best outcomes for pediatric trauma patients. Using a multidisciplinary approach, CPTR researchers lead innovative projects to assess pre-hospital emergency medical service, acute medical and surgical management, rehabilitation, and family and community services that impact the short and long-term outcomes of injured patients. CPTR serves as a leader and a partner to translate cutting edge research findings to help patients, families, policy makers, and clinicians make informed decisions.


Symposium Objectives

  • Describe methodological challenges in trauma research
  • Discuss advances in research methods with applicability in trauma
  • Explore emerging technological trends in trauma care and research


8:00 – 8:45 AM | Registration and Continental Breakfast

8:45 – 9:00 AM | Welcome
Henry Xiang, MD, MPH, PhD, Dennis Durbin, MD & William Martin II, MD 

9:00 – 10:00 AM | Methodological Challenges: The State of Trauma Research
Monica S. Vavilala, MD – Keynote Speaker

SESSION 1: Causal Inference Methods for Observational and Medical Record Data

Introductions – Steve MacEachern, PhD

10:00 – 11:00 AM | Causal Inference in Experiments and Observational Studies
Donald B. Rubin, PhD – Keynote Speaker

11:00 – 11:15 AM | Break & Poster Viewing

11:15 – 11:45 AM | Model Assisted Sensitivity Analyses for Hidden Bias in Evaluating Mortality Differences across Multiple Trauma Center Levels
Bo Lu, PhD

11:45 AM – 12:15 PM | Individual Patient Data Meta-Analysis of Collections of Trials on Behavioral Treatments for Pediatric Traumatic Brain Injury
Eloise Kaizar, PhD

12:15 – 1:30 PM | Lunch

SESSION 2: Cohort and Longitudinal Data Analytic Approaches

Introductions – Bo Lu, PhD

1:30 – 2:30 PM | Advances in Longitudinal Data Analysis
Donald Hedeker, PhD – Keynote Speaker

2:30 – 3:00 PM | Personalized Predictive Probabilities of Rapid Disease Progression using the Cystic Fibrosis Foundation Patient Registry
Rhonda Szczesniak, PhD

3:00 – 3:15 AM | Break & Poster Viewing

3:15 – 3:45 PM | Use of g-methods for CER based on longitudinal observational data
Yi Zhang, PhD, MS

3:45 – 4:15 PM | Panel Discussion/ Q&A

4:15 – 5:15 PM | Reception & Optional Nationwide Children’s Hospital Tours
Larry Moss, MD

8:00 – 8:45 AM | Registration and Continental Breakfast

SESSION 3: Adaptive Clinical Trial Design,  Imaging, and Virtual Reality

Introductions – Henry Xiang, MD, MPH, PhD

8:45 – 9:45 AM | Utility Based Bayesian Clinical Trial Design
Peter F. Thall, PhD – Keynote Speaker

9:45 – 10:15 AM | Utility of Neuroimaging Approaches in Pediatric Brain Trauma Research
Eric Nelson, PhD

10:15 – 10:45 AM | Break & Poster Viewing

10:45 – 11:15 AM | Designing a Study for Training Data Collection for a Burn Detection Algorithm
Amy Nussbaum, PhD

11:15 – 11:45 AM | Using a VR-based Pain Alleviation Tool (VR-PAT) for Pediatric Outpatient Burn Patients
Jiabin Shen, PhD

11:45 AM – 12:00 PM | Closing Remarks
Henry Xiang, MD, MPH, PhD


Keynote Speakers

Donald Hedeker, PhD
Donald Hedeker, PhDChicago, IL, USA
Department of Public Health Sciences & Department of Medicine, The University of Chicago Biological Sciences
Donald B. Rubin, PhD
Donald B. Rubin, PhDCambridge, MA, USA
Department of Statistics,
Harvard University
Peter F. Thall, PhD
Peter F. Thall, PhDHouston, TX, USA
Department of Biostatistics, M.D. Anderson Cancer Center, The University of Texas
Monica S. Vavilala, MD
Monica S. Vavilala, MDSeattle, WA, USA
Harborview Injury Prevention and Research Center, The University of Washington

Honored Guests

John A. Barnard, MD
John A. Barnard, MDColumbus, OH, USA
President, The Research Institute at
Nationwide Children’s Hospital
William Martin II, MD
William Martin II, MDColumbus, OH, USA
Dean, The Ohio State University,
College of Public Health
Dean C. Manderscheid, PHD
Dean C. Manderscheid, PHDColumbus, OH, USA
Executive Dean, The Ohio State University,
College of Arts and Sciences
R. Lawrence Moss, MD
R. Lawrence Moss, MDColumbus, OH, USA
Surgeon- in- Chief,
Nationwide Children’s Hospital

Planning Committee

Henry Xiang, MD, MPH, PHD
Henry Xiang, MD, MPH, PHD Conference Chair
Director of Center for Pediatric Trauma Research, Professor of Medicine,
The Research Institute at Nationwide Children’s Hospital

 Bo Lu, PhD
Bo Lu, PhDConference Co-Chair
Associate Professor, Division of Biostatistics,
College of Public Health, The Ohio State University
Steve MacEachern, PhD
Steve MacEachern, PhDConference Co-Chair
Professor, Chair of Department of Statistics,
College of Arts and Sciences, The Ohio State University

Gail E. Besner, MD
Gail E. Besner, MD
Jonathan I. Groner, MD
Jonathan I. Groner, MD
Kathy Haley, RN, BSN, MS
Kathy Haley, RN, BSN, MS
Julie C. Leonard, MD, MPH
Julie C. Leonard, MD, MPH
Eric A. Sribnick, MD, PhD
Eric A. Sribnick, MD, PhD
Rachel M. Stanley, MD
Rachel M. Stanley, MD
Rajan K. Thakkar, MD
Rajan K. Thakkar, MD
Jingzhen 'Ginger' Yang, PhD, MPH
Jingzhen 'Ginger' Yang, PhD, MPH

Symposium Sponsors

The Childress Institute for Pediatric Trauma
The Childress Institute for Pediatric Trauma
Nationwide Children’s Hospital
Center for Pediatric Trauma Research
Center for Injury Research and Policy
Trauma Program
Department of Pediatric Surgery
The Ohio State University
College of Arts & Sciences
College of Public Health

Submission of Abstracts

Oral abstracts will be presented in the following categories:

  • Observational and Medical Record Data
  • Causal Inference Methods
  • Cohort and Longitudinal Data Analytic Approaches
  • Adaptive Clinical Trial Design
  • Advances in Imaging
  • Technology-Assisted Interventions (e.g. Virtual Reality)

Online Submission of abstracts is now closed. The deadline was March 15, 2018.

Travel & Accomodations

About the Hotel

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Hilton Columbus Downtown

Rooms are available at the Hilton Columbus Downtown at a discounted rate of $179 USD + tax for Single or Double Occupancy. In order to receive this discounted rate, room reservations must be made no later than May 18, 2018.

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Hilton Columbus Downtown offers a contemporary presence in the eclectic hub of Columbus. Explore our $1 million art collection featuring original works from more than 100 area artists. Our Columbus, OH hotel is within walking distance to over 300 dining and entertainment venues. Take our unique spiral staircase for dining and fitness options. Unwind over dinner and drinks at our Gallerie Bar.

A complimentary shuttle will be making round trips from the Hilton to the Hospital education center during designated times.

Getting to Columbus

John Glenn Columbus International Airport, located just 15 minutes from the Sheraton, is served by 10 airlines and their regional affiliates, providing 350 daily arrivals and departures serving 35 destinations on a non-stop basis and hundreds of additional cities on a direct or connecting basis. Major carriers include AirTran, Air Canada Express, American, American, Delta, Southwest, United and US Airways. All ground transportation may be accessed via the terminal walkway or baggage claim levels.

From John Glenn Columbus International Airport, the best mode of transportation is via taxi readily available 24-hours a day at the cab stand outside baggage claim. The 15-minute ride should run around $25 inclusive. The hotel does not have an airport shuttle.

Columbus also offers Uber car services as well as a number of private scheduled sedan services including Cardinal Transportation.

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